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The hormone Aldosterone is known to regulate essential salts and blood pressure in the body, but Aldosterone secretion may also hold the key to loss of hearing.
The body’s sodium (salt), potassium and water levels are kept in equilibrium through aldosterone secreted by the adrenal gland. Known as the body’s electrolytes, these same essential salts may be a factor in hearing loss. This is because sodium and potassium levels – regulated as we know by Aldosterone - are also crucial to our hearing, hence the Aldosterone hearing loss correlation. The inner ear, which is often linked with the sensorineural hearing loss condition, is particularly sensitive to Aldosterone levels.
The all important balance of Aldosterone in the body is underlined by the medical condition Hyperaldosteronism. Characterised by high blood pressure and fatigue, Hyperaldosteronism is caused by the production of too much Aldosterone, which in turn lowers potassium levels in the blood.
In addition to Hyperaldosteronism, Aldosterone levels play a part in the function of the antidiuretic hormone (adh for short), which regulates the uptake and use of water by the body. The levels of adh and Aldosterone are therefore inextricably linked: part of the delicate balance of salt and water in humans.
In the area of Aldosterone deficiency and hearing loss, the work of Dr Jonathan Wright in the US has looked beyond treatments such as hearing aids and surgery to consider the Aldosterone factor.
Dr Jonathan Wright took an active interest in Aldosterone following research into what causes hearing loss in older people by the International Center for Hearing and Speech Research (ICHSR). The ICHSR is a recognised leader in loss of hearing and acute hearing loss.
An Aldosterone potassium link to the aging process has been established, as it’s known that both potassium and Aldosterone levels decline with age (falling levels of potassium in particular being a factor in age related loss of hearing).
However, in 2005 the ICHSR research team demonstrated a direct link between low blood levels of Aldosterone and loss of hearing. The Aldosterone hearing loss conclusion followed a study of older men and women between 58 and 84, which included extensive hearing tests and the measurement of Aldosterone levels in the blood. Not only did the study find that hearing improved in relation to the amount of Aldosterone in the body, but that people with acute loss of hearing had just half the Aldosterone blood levels as those with normal hearing.
Following these findings, an Aldosterone hearing loss treatment regime was established by Dr Jonathan Wright at his clinic. Similar Aldosterone hearing loss work has also been carried out by Belgian antiaging hormone treatment specialist Dr Thierry Hertpghe.
The movement to address Aldosterone deficiency in age related loss of hearing represents a real advance in treatment options, and a far less intrusive alternative to hearing aids.
The aging process is just one of the underlying causes of hearing loss, though conditions like sensorinueural hearing loss and tinnitus can cause problems at any age, including hearing loss in children. And although rare, child hearing loss has been related to the Hyperaldosteronism condition and over-production of aldosterone.
From child hearing loss to age related loss of hearing, through hearing loss in one ear to ringing in ears and tinnitus – the symptoms of hearing loss range from mild to acute.
Looking beyond age related hearing problems, knowledge of Aldosterone brings hope for a variety of hearing problems, including AIED (autoimmune inner ear disease) and Meniere’s disease – a debilitating condition of the inner ear characterised by problems with balance, vertigo and constant ear noise / tinnitus.
Taken alongside everyday precautions to safeguard our hearing - such as keeping headphone levels down on personal devices – an Aldosterone supplement is both simple and safe to administer. A typical dosage is one Aldosterone capsule 1 or 2 times daily.
Aldosterone’s important role in maintaining the body’s delicate balance of water and essential salts not only impacts on our blood pressure health. As a treatment for hearing loss, Aldosterone also offers a viable alternative to hearing aids and surgery.
Chemical Aldosterone hormone.
Package 5 ml bottle containing a total of 10 mg aldosterone and a proprietary mix of vegetable oils.
Properties Aldosterone is a steroid hormone of the mineral corticoid family and is produced by the outer section (zona glomerulosa) of the adrenal cortex in the adrenal gland. It plays a central role in regulation of hearing acting on the rows of hair cells in the cochlea. It also plays a central role regulating blood pressure by acting on the distal tubules and collecting ducts of the nephron, increasing reabsorption of ions and water in the kidney, to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. High levels of aldosterone are associated with cardiovascular and renal disease, and thus, it should be measured regularly in blood and urine tests.
Directions Apply one spray to each ear canal only once daily by tilting the head to the side (each spray is 125 micrograms). The maximum daily allowance for adults is 250 micrograms per ear canal. The maximum dosage to be given at one time is 125 micrograms per ear canal. Check blood pressure. Antihypertensive drugs interfere with the action of aldosterone. Aldo-Spray™ may also be applied topically to the skin to improve the appearance of periorbital rhytids or crow’s feet. Aldo-Spray™ may also be used nasally to prevent rhinitis and a systemic aldosterone deficiency. Before bedtime, one should gently clean the ear canals with a cotton swab or bud or by washing them with soap and water.
Caution Do not press the spray nozzle deep into the ear canal and against the eardrum. Do not spray more than one spray per ear canal. More than one spray per ear canal may cause sensitively to loud sounds in the environment, such as background music or the sirens from ambulances. Although the hypertensive action of aldosterone is minimal when applied in the ear canal and in normal doses, it should be administered with caution if increased blood pressure is to be avoided. In cases of hypertension, advanced arteriosclerosis and epilepsy, this product should not be used.
Contraindications Coronary insufficiency, halothane or cyclopropane anesthetic.
Interactions Aldosterone is incompatible with all antihypertensive medications and with meds that interfere or block the angiotensin-converting enzyme (ACE).
Side Effects: Side effects of a general nature are related to the hypertensive activity described under ‘caution’. With normal physiologic doses of 125 micrograms or less, side effects are very mild or non-existent. Occasionally, it may produce ear canal itchiness if the ear canal is infected with fungus. Occasionally, it may cause headaches, conjunctivitis, sore throat, nausea, and abdominal pain especially if not used as directed.
Intoxication and its treatment: Symptoms of intoxication appear following the taking of very high doses, causing gastrointestinal upsets, intestinal hypermotility, increased blood pressure, collapse, stenocardiac disorders, cold sweats, pallor, problems in renal functioning, convulsions if there is already a predisposition, (for example, in the cases of epilepsy and ecampsia), and eventual uterine tetanization if taken during pregnancy. Treatment- Symptomatic therapy is only necessary in extreme cases: control of the circulatory system, or the hydrosaline metabolism and diuresis.
Presentation and use In cases of itching ear canals caused by fungus, one must first treat with an antifungal remedy such as Nystatin© or ProEar™. Upon clearing the ear canal of fungus, apply the 5 ml spray bottle containing Aldo-Spray™ by (1) Remove cap and squeezing 3 times before the first spray. (2) Tilt the head to the side and introduce the spray bottle vertically into one ear canal and squeeze once. The patient should use a finger to gently press the opening of the ear canal for improved spray distribution. (3) Replace cap after use.
Storage: The preparation may be kept at room temperature providing it is in a cool and dry place out of sunlight; it can also be kept in the cooler part of a fridge (i.e. the door). Once opened use and discard after three months.
Precautions: Keep this and all other medicines out of the reach of children. This product is not intended for use by pregnant or lactating women. This information does not replace your physician’s advice, always seek and follow your physician’s advice.